Article
Association of ERAP1 Gene Polymorphisms With Behçet's Disease in Han Chinese.
Investigative ophthalmology & visual science - 1 Sept 2015
Zhang Lijun, Yu Hongsong, Zheng Minming, Li Hua, Liu Yunjia, Kijlstra Aize, Yang Peizeng
Abstract excerpt
PURPOSE: Behçet's disease (BD) is a common uveitis entity in China. The endoplasmic reticulum aminopeptidase 1 (ERAP1), has a significant influence on the stability and immunological properties of MHC-I loaded peptides. In the present study, we investigated the association of ERAP1 gene polymorphisms with BD in a Chinese Han population. METHODS: A two-stage case-control study was carried out in 930 BD patients...
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