Article
SUMO4 gene polymorphisms in Chinese Han patients with Behcet's disease.
Clinical immunology (Orlando, Fla.) - 1 Oct 2008
Hou Shengping, Yang Peizeng, Du Liping, Zhou Hongyan, Lin Xiaomin, Liu Xiaoli, Kijlstra Aize
Abstract excerpt
Small ubiquitin-like modifier 4 (SUMO4) has been shown to have the potential to down-regulate NF-kappaB signal, leading to decreased transcription of pro-inflammatory cytokines. Recently, SUMO4 polymorphisms have been shown to be associated with several autoimmune diseases. In the present study, the association of SUMO4 polymorphisms with Behcet's disease (BD) was investigated. Our results showed a significantly...
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