Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Quantitative assessment of common genetic variants on FOXE1 and differentiated thyroid cancer risk.

PloS one - 1 Jan 2014

Zhu Hongling, Xi Qian, Liu Lianyong, Wang Jingnan, Gu Mingjun

Abstract excerpt

Forkhead box E1 encodes the transcription factor FOXE1 (or TTF-2), which together with Homeobox protein NKX2-1, PAX8 and HHEX, are pivotal proteins required for thyroid gland formation, differentiation and function. Recently, genome-wide association studies have identified FOXE1 as a thyroid cancer (TC) susceptibility gene in populations of European descent. After that, a number of studies reported that the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies
Share to Forkhead Transcription Factors
Share to Gene Frequency

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Genome-Wide Association Study

Share to Polymorphism, Single Nucleotide

Share to Risk Factors

Share to Thyroid Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 24489898
DOI: 10.1371/journal.pone.0087332
PMCID: PMC3906140

Genes

FOXE1
HHEX
PAX8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Quantitative assessment of common genetic variants on FOXE1 and differentiated thyroid cancer risk.PMID 24489898Read ↗

Common genetic variants on FOXE1 contributes to thyroid cancer susceptibility: evidence based on 16 studies.Semantic proximity Read ↗

Exploration of the association between FOXE1 gene polymorphism and differentiated thyroid cancer: a meta-analysis.Semantic proximity Read ↗

rs965513 polymorphism as a common risk marker is associated with papillary thyroid cancer.Semantic proximity Read ↗

FOXE1 association with differentiated thyroid cancer and its progression.Semantic proximity Read ↗

Relationships of FOXE1 and ATM genetic polymorphisms with papillary thyroid carcinoma risk: a meta-analysis.Semantic proximity Read ↗

The investigation of foxe1 variations in papillary thyroid carcinoma.Semantic proximity Read ↗

The FOXE1 rs965513 polymorphism: a pleiotropic risk locus associated with thyroid function, BRAFV600E mutation, and susceptibility to papillary thyroid cancer.Semantic proximity Read ↗

The Contribution of Genetic Variants to the Risk of Papillary Thyroid Carcinoma in the Kazakh Population: Study of Common Single Nucleotide Polymorphisms and Their Clinicopathological Correlations.Semantic proximity Read ↗

Novel genome-wide association study-based candidate loci for differentiated thyroid cancer risk.Semantic proximity Read ↗

The variant rs1867277 in FOXE1 gene confers thyroid cancer susceptibility through the recruitment of USF1/USF2 transcription factors.Semantic proximity Read ↗

The FOXE1 and NKX2-1 loci are associated with susceptibility to papillary thyroid carcinoma in the Japanese population.Semantic proximity Read ↗

Thyroid cancer GWAS identifies 10q26.12 and 6q14.1 as novel susceptibility loci and reveals genetic heterogeneity among populations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.