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Role of p53 gene polymorphism and bladder cancer predisposition in northern India.

Cancer biomarkers : section A of Disease markers - 1 Jan 2010

Srivastava Priyanka, Jaiswal Praveen K, Singh Vibha, Mittal Rama D

Abstract excerpt

p53 is a major orchestrator of cellular response to a broad array of stress types by regulating apoptosis, cell cycle arrest, etc. A few polymorphic sites, one at codon72 of exon4, intron3 16bpdel/ins, intron6G>A have been studied with regard to Bladder cancer (BC) risk in North Indians. Genotypes were assessed in hospital-based case-control study comprising of 200BC cases, 265healthy controls. After extraction...

Topics

BCG Vaccine
Female
Genetic Predisposition to Disease
Haplotypes
Humans
Immunotherapy
India
Male
Middle Aged
Polymorphism, Genetic
Smoking
Urinary Bladder Neoplasms

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Identifiers

PMID: 21896987
DOI: 10.3233/DMA-2011-0816
PMCID: PMC12994712

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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