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Article

Genetic basis of end-stage hypertrophic cardiomyopathy.

European journal of heart failure - 1 Nov 2011

Garcia-Pavia Pablo, Vázquez Maria E, Segovia Javier, Salas Clara, Avellana Patricia, Gómez-Bueno Manuel, Vilches Carlos, Gallardo M Esther, Garesse Rafael, Molano Jesús, Bornstein Belén, Alonso-Pulpon Luis

Abstract excerpt

AIMS: Hypertrophic cardiomyopathy (HCM) is characterized by a heterogeneous presentation and clinical course. A minority of HCM patients develop end-stage HCM and require cardiac transplantation. The genetic basis of end-stage HCM is unknown but small series, isolated case reports and animal models have related the most aggressive heart failure course with the presence of multiple mutations. METHODS AND RESULTS:...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21896538
DOI: 10.1093/eurjhf/hfr110

Genes

LAMP2
MYBPC3
MYH7
MYL2
MYL3
TNNI3
LDB3
PRKAG2
TNNC1
TNNT2
TPM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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