Article

Genetic Spectrum, Clinical Characteristics, and Molecular Pathogenesis of Hypertrophic Cardiomyopathy Requiring Heart Transplantation

2025-10-02

Abstract excerpt

Hypertrophic cardiomyopathy (HCM) progressing to end-stage heart failure and heart transplantation (HT) is a rare clinical scenario with insufficiently explored genetic background. In this single-center retrospective cohort study we aimed to characterize the genetic spectrum, variants of HCM adverse remodeling, and aspects of molecular pathogenesis of this subgroup. The study included 14 patients (9 females), amon...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 979b0ffa-93fb-550f-8b38-4d00d4d6808d
DOI: 10.20944/preprints202510.0140.v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Genetic Spectrum, Clinical Characteristics, and Molecular Pathogenesis of Hypertrophic Cardiomyopathy Requiring Heart TransplantationDOI 10.20944/preprints202510.0140.v1Read

Phenotypes of hypertrophic cardiomyopathy: genetics, clinics, and modular imaging.Semantic proximity Read

Hypertrophic cardiomyopathy: pathological features and molecular pathogenesis.Semantic proximity Read

Genetic basis of end-stage hypertrophic cardiomyopathy.Semantic proximity Read

Hypertrophic Cardiomyopathy in Underrepresented Populations: Clinical and Genetic Landscape Based on Russian Single-Center Cohort StudySemantic proximity Read

Hypertrophic Cardiomyopathy in Underrepresented Populations: Clinical and Genetic Landscape Based on a Russian Single-Center Cohort StudySemantic proximity Read

Hypertrophic Cardiomyopathy: An Overview of Genetics and ManagementSemantic proximity Read

Hypertrophic Cardiomyopathy: Genetics, Pathogenesis, Clinical Manifestations, Diagnosis, and Therapy.Semantic proximity Read

Hypertrophic cardiomyopathy. Distribution of disease genes, spectrum of mutations, and implications for a molecular diagnosis strategySemantic proximity Read

Role of Genetics in Diagnosis and Management of Hypertrophic Cardiomyopathy: A Glimpse into the FutureSemantic proximity Read

Hypertrophic Cardiomyopathy: Genetic Foundations, Outcomes, Interconnections, and Their ModifiersSemantic proximity Read

Genetics of hypertrophic cardiomyopathy: advances and pitfalls in molecular diagnosis and therapySemantic proximity Read

Genetics of hypertrophic cardiomyopathy: A review of current state.Semantic proximity Read