Article
Shared genetic causes of cardiac hypertrophy in children and adults.
The New England journal of medicine - 1 May 2008
Morita Hiroyuki, Rehm Heidi L, Menesses Andres, McDonough Barbara, Roberts Amy E, Kucherlapati Raju, Towbin Jeffrey A, Seidman J G, Seidman Christine E
Abstract excerpt
BACKGROUND: The childhood onset of idiopathic cardiac hypertrophy that occurs without a family history of cardiomyopathy can portend a poor prognosis. Despite morphologic similarities to genetic cardiomyopathies of adulthood, the contribution of genetics to childhood-onset hypertrophy is unknown. METHODS: We assessed the family and medical histories of 84 children (63 boys and 21 girls) with idiopathic cardiac...
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