Article
The CDKN2A p.A148T variant is associated with cutaneous melanoma in Southern Brazil.
Experimental dermatology - 1 Nov 2011
Bakos Renato M, Besch Robert, Zoratto Gabriela G, Godinho Janaína M, Mazzotti Nicolle G, Ruzicka Thomas, Bakos Lucio, Santos Sidney E, Ashton-Prolla Patricia, Berking Carola, Giugliani Roberto
Abstract excerpt
Several germline mutations and sequence variants in cancer predisposition genes have been described. Among these, the CDKN2A p.A148T variant appears to be frequent in patients with melanoma, at least in certain ethnic groups. In this case-control study, we evaluated 127 patients with cutaneous melanoma and 128 controls from Southern Brazil, the region with the highest melanoma incidence rates in the country....
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