CDKN2A common variant and multi-organ cancer risk--a population-based study.

doi:10.1002/ijc.21760

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Article

CDKN2A common variant and multi-organ cancer risk--a population-based study.

International journal of cancer - 15 Jun 2006

Debniak Tadeusz, Scott Rodney J, Huzarski Tomasz, Byrski Tomasz, Rozmiarek Andrzej, Debniak Boguslaw, Górski Bohdan, Cybulski Cezary, Medrek Krzysztof, Mierzejewski Marek, Masojc Bartłomiej, Matyjasik Joanna, Złowocka Elzbieta, Teodorczyk Urszula, Lener Marcin, Klujszo-Grabowska Ewa, Nej-Wołosiak Katarzyna, Jaworowska Ewa, Oszutowska Dorota, Szymańska Anna, Szymańska Jolanta, Castaneda Jennifer, van de Wetering Thierry, Suchy Janina, Kurzawski Grzegorz, Oszurek Oleg, Narod Steven, Lubinski Jan

Abstract excerpt

The population frequencies of the CDKN2A common variants remain undetermined. In Poland, there is a common variant of the CDKN2A: an alanine to threonine substitution (A148T), which has been detected in other populations. We have recently showed that it is significantly overrepresented among Polish melanoma patients when compared to general population. Herein, we ascertained the prevalence of the A148T variant in...

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PMID: 16395703
DOI: 10.1002/ijc.21760

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