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Article

CDKN2A and CDK4 variants in Latvian melanoma patients: analysis of a clinic-based population.

Melanoma research - 1 Jun 2007

Pjanova Dace, Engele Ludmila, Randerson-Moor Juliette A, Harland Mark, Bishop D Timothy, Newton Bishop Julia A, Taylor Claire, Debniak Tadeusz, Lubinski Jan, Kleina Regina, Heisele Olita

Abstract excerpt

Germline mutations of the CDKN2A and CDK4 genes explain a significant proportion of familial melanoma. To date, there have been few published estimations of the prevalence of such mutations in sporadic melanoma patients. In this study, we investigated CDKN2A and CDK4 exon 2 for germline mutations in 125 consecutive cutaneous malignant melanoma patients recruited through the Latvian Oncological Center, using...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17505264
DOI: 10.1097/CMR.0b013e328014a2cd

Genes

CDK4

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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