Article
Recent genomic advances in schizophrenia.
Clinical genetics - 1 Feb 2012
Doherty J L, O'Donovan M C, Owen M J
Abstract excerpt
Recent studies have supported the hypothesis based upon expectations from population genetics that the high heritability of schizophrenia reflects a combination of relatively common alleles of small effect and rare alleles some with relatively large effects. Genome-wide association studies have identified a number of risk loci at genome-wide levels of significance as well as evidence for a substantial burden of...
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