Article
Schizophrenia genetics: advancing on two fronts.
Current opinion in genetics & development - 1 Jun 2009
Owen Michael J, Williams Hywel J, O'Donovan Michael C
Abstract excerpt
Recent studies have supported the hypothesis that the high heritability of schizophrenia reflects a combination of relatively common alleles of small effect and some rare alleles with relatively large effects. Genome-wide association studies have identified at least one common allele of small effect at ZNF804a, which encodes a putative zinc finger binding protein, as well as possible roles for other loci. The...
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