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Article

Molecular and genetic evidence for abnormalities in the nodes of Ranvier in schizophrenia.

Archives of general psychiatry - 1 Jan 2012

Roussos Panos, Katsel Pavel, Davis Kenneth L, Bitsios Panos, Giakoumaki Stella G, Jogia Jigar, Rozsnyai Kinga, Collier David, Frangou Sophia, Siever Larry J, Haroutunian Vahram

Abstract excerpt

CONTEXT: Genetic, neuroimaging, and molecular neurobiological evidence support the hypothesis that the disconnectivity syndrome in schizophrenia (SZ) could arise from failures of saltatory conduction and abnormalities at the nodes of Ranvier (NOR) interface where myelin and axons interact. OBJECTIVE: To identify abnormalities in the expression of oligodendroglial genes and proteins that participate in the...

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Source

Identifiers

PMID: 21893642
DOI: 10.1001/archgenpsychiatry.2011.110

Genes

ANK3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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