Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Hedgehog signalling promotes germ cell survival in the rat testis

5 Sept 2011

Abstract excerpt

Hedgehog (Hh) signalling has a crucial role in testis development. Sertoli cell-derived desert hedgehog (DHH) guides the formation of testis cords and differentiation of foetal-type Leydig cells. Dhh mutant mice are infertile due to a block in germ cell differentiation, hypogonadism and hypoandrogenism. Hh signalling pathway components are also expressed in postnatal testis. In the rat testis the transcription...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ethics and Legal Issues in Pediatric Healthcare
Share to Hedgehog Signaling Pathway Studies
Share to Testicular diseases and treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 21893610
DOI: 10.1530/rep-11-0110

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Hedgehog signalling promotes germ cell survival in the rat testisPMID 21893610Read ↗

Dynamic Hedgehog signalling pathway activity in germline stem cellsSemantic proximity Read ↗

Expression of hedgehog signalling components in adult mouse testis.Semantic proximity Read ↗

Role of the Hedgehog Signaling Pathway in Regulating the Behavior of Germline Stem CellsSemantic proximity Read ↗

Sertoli cell signaling by Desert hedgehog regulates the male germline.Semantic proximity Read ↗

Cell interactions and genetic regulation that contribute to testicular Leydig cell development and differentiationSemantic proximity Read ↗

The sonic hedgehog-GLI1 signaling pathway in brain tumor developmentSemantic proximity Read ↗

Smoothened mediates medaka spermatogonia proliferation via Gli1–Rgcc–Cdk1 axisSemantic proximity Read ↗

Hh signalling is essential for somatic stem cell maintenance in the Drosophila testis niche.Semantic proximity Read ↗

Mutations in the desert hedgehog (DHH) gene in the disorders of sexual differentiation and male infertility.Semantic proximity Read ↗

Identification of Hedgehog Signaling Outcomes in Mouse Testis Development Using a Hanging Drop-Culture System1Semantic proximity Read ↗

Redundant and Differential Roles of Transcription Factors Gli1 and Gli2 in the Development of Mouse Fetal Leydig Cells1Semantic proximity Read ↗

Growth regulatory factors and signalling proteins in testicular germ cell tumoursSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.