Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Sertoli cell signaling by Desert hedgehog regulates the male germline.

Current biology : CB - 1 Mar 1996

Bitgood M J, Shen L, McMahon A P

Abstract excerpt

BACKGROUND: In mammals, testis development is initiated in the embryo in response to the expression of the sex determining gene, Sry, in Sertoli cell precursors. Subsequently, Sertoli cells are thought to play a central role in male-specific cell interactions, including those that occur during sp...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Gene Expression Regulation
Share to Membrane Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mice, Inbred C57BL

Share to Proteins

Share to Signal Transduction

Share to Trans-Activators

Source

Identifiers

PMID: 8805249
DOI: 10.1016/s0960-9822(02)00480-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Prepared record publication-8805249-2026-09-05.1. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Sertoli cell signaling by Desert hedgehog regulates the male germline.PMID 8805249Read ↗

Desert hedgehog (Dhh) gene is required in the mouse testis for formation of adult-type Leydig cells and normal development of peritubular cells and seminiferous tubules.Semantic proximity Read ↗

Lrh1 can help reprogram sexual cell fate and is required for Sertoli cell development and spermatogenesis in the mouse testisSemantic proximity Read ↗

Unveiling the roles of Sertoli cells lineage differentiation in reproductive development and disorders: a reviewSemantic proximity Read ↗

Genetic Control of Testis DevelopmentSemantic proximity Read ↗

Male sex determination: insights into molecular mechanismsSemantic proximity Read ↗

Hedgehog signalling promotes germ cell survival in the rat testisSemantic proximity Read ↗

Dynamic Hedgehog signalling pathway activity in germline stem cellsSemantic proximity Read ↗

The mammalian Doublesex homolog DMRT6 coordinates the transition between mitotic and meiotic developmental programs during spermatogenesis.Semantic proximity Read ↗

Expression profiling of purified mouse gonadal somatic cells during the critical time window of sex determination reveals novel candidate genes for human sexual dysgenesis syndromesSemantic proximity Read ↗

Regulation of male sex determination: genital ridge formation and Sry activation in miceSemantic proximity Read ↗

Turning on the male--SRY, SOX9 and sex determination in mammals.Semantic proximity Read ↗

Distinct Roles for Steroidogenic factor 1 and Desert hedgehog Pathways in Fetal and Adult Leydig Cell DevelopmentSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.