Article
Sertoli cell signaling by Desert hedgehog regulates the male germline.
Current biology : CB - 1 Mar 1996
Bitgood M J, Shen L, McMahon A P
Abstract excerpt
BACKGROUND: In mammals, testis development is initiated in the embryo in response to the expression of the sex determining gene, Sry, in Sertoli cell precursors. Subsequently, Sertoli cells are thought to play a central role in male-specific cell interactions, including those that occur during spermatogenesis. However, the molecular nature of these interactions is poorly understood. Desert hedgehog (Dhh) encodes...
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