Article
Expression patterns of two potassium channel genes in skeletal muscle cells of patients with familial hypokalemic periodic paralysis.
Neurology India - 1 Jan 2000
Kim June-Bum, Lee Gyung-Min, Kim Sung-Jo, Yoon Dong-Ho, Lee Young-Hyuk
Abstract excerpt
BACKGROUND: Familial hypokalemic periodic paralysis is an autosomal-dominant disorder characterized by episodic attacks of muscle weakness with hypokalemia. The combination of sarcolemmal depolarization and hypokalemia has been attributed to abnormalities of the potassium conductance governing the membrane potential; however, the molecular mechanism that causes hypokalemia has not yet been determined. AIM: To...
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