Article
Thyrotoxic Hypokalemic Periodic Paralysis: Pathophysiological Mechanisms.
Endocrinology and metabolism (Seoul, Korea) - 1 Dec 2025
Qing Gan, Zakaria Wan Nur Amalina, Rom Fatimah Zahra Mohamad, Nik Wan Nor Fazila Hafizan Wan, Zulkeflee Hani Ajrina, Rahim Siti Nadirah Ab
Abstract excerpt
Thyrotoxic hypokalemic periodic paralysis (THPP) is a rare but potentially fatal complication of thyrotoxicosis, characterized by transient episodes of muscle weakness in the setting of hypokalemia and underlying hyperthyroidism. Although thyrotoxicosis is more common in females, THPP predominantly affects males, especially in Asian populations, in which its prevalence is notably higher. Early recognition is...
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