Monocyte phenotype and cytokine production profiles are dysregulated by short-duration spaceflight.

doi:10.3357/asem.3047.2011

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Article

Monocyte phenotype and cytokine production profiles are dysregulated by short-duration spaceflight.

Aviation, space, and environmental medicine - 1 Sept 2011

Crucian Brian, Stowe Raymond, Quiriarte Heather, Pierson Duane, Sams Clarence

Abstract excerpt

INTRODUCTION: Immune system dysregulation has been demonstrated to occur during and immediately following spaceflight. As the initial bias and magnitude for an immune response is heavily influenced by monocyte/macrophage secreted cytokines, this study investigated monocyte phenotype and cytokine production patterns following short-duration spaceflight. METHODS: Secreted cytokine profiles were examined by...

Topics

Female
Granulocytes
Humans
Immune System
Immunocompetence
Immunomagnetic Separation
Immunophenotyping
L-Selectin
Lymphocytes
Male
Middle Aged
Monocytes
Phenotype
Space Flight
Weightlessness

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Open in PubMed

Identifiers

PMID: 21888268
DOI: 10.3357/asem.3047.2011

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