Article
Identification of distinct monocyte phenotypes and correlation with circulating cytokine profiles in acute response to spinal cord injury: a pilot study.
PM & R : the journal of injury, function, and rehabilitation - 1 Apr 2014
Huang Wan, Vodovotz Yoram, Kusturiss Mary B, Barclay Derek, Greenwald Karen, Boninger Michael L, Coen Paul M, Brienza David, Sowa Gwendolyn
Abstract excerpt
BACKGROUND: Macrophage infiltration to the injury site during the acute response to traumatic spinal cord injury (SCI) is not uniform. Macrophage phenotype has been characterized as either proinflammatory (M1) or anti-inflammatory (M2). Results of animal studies suggest that M1 or M2 dominance at the site of injury relates to spontaneous recovery after SCI. OBJECTIVE: To investigate whether the phenotype of...
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