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Article

B cell signature during inactive systemic lupus is heterogeneous: toward a biological dissection of lupus.

PloS one - 1 Jan 2011

Garaud Jean-Claude, Schickel Jean-Nicolas, Blaison Gilles, Knapp Anne-Marie, Dembele Doulaye, Ruer-Laventie Julie, Korganow Anne-Sophie, Martin Thierry, Soulas-Sprauel Pauline, Pasquali Jean-Louis

Abstract excerpt

Systemic lupus erythematosous (SLE) is an autoimmune disease with an important clinical and biological heterogeneity. B lymphocytes appear central to the development of SLE which is characterized by the production of a large variety of autoantibodies and hypergammaglobulinemia. In mice, immature B cells from spontaneous lupus prone animals are able to produce autoantibodies when transferred into immunodeficient...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21886837
DOI: 10.1371/journal.pone.0023900
PMCID: PMC3160348

Genes

EGR1
PMEPA1
TLR10

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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