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Article

Developments in the scientific understanding of lupus.

Arthritis research & therapy - 1 Jan 2008

Ardoin Stacy P, Pisetsky David S

Abstract excerpt

Systemic lupus erythematosus is a systemic autoimmune disease characterized by the production of antinuclear antibodies (ANAs). Recent research into human and murine lupus suggests that disease susceptibility results from genetic polymorphisms regulating immune responses as well as impairing the clearance of apoptotic cells. Because the products of dead cells, including nucleic acids, have immunologic activity,...

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Identifiers

PMID: 18947369
DOI: 10.1186/ar2488
PMCID: PMC2592776

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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