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Article

A host range mutant of Newcastle disease virus with an altered cleavage site for proteolytic activation of the F protein.

Virus research - 1 Mar 1990

Pritzer E, Kuroda K, Garten W, Nagai Y, Klenk H D

Abstract excerpt

The primary structure of the F protein of a host range mutant of the Ulster strain of Newcastle Disease virus (NDV) has been determined by nucleotide sequence analysis and compared to that of the wild type and other NDV strains. The cleavage site of the mutant had the sequence Gly-Lys-Gln-Arg-Arg as compared to two isolated basic amino acids [Gly-Lys(Arg)-Gln-Gly-Arg] with the apathogenic strains and two pairs of...

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PMID: 2188464
DOI: 10.1016/0168-1702(90)90031-6

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