Article
The effect on pathogenesis of Newcastle disease virus LaSota strain from a mutation of the fusion cleavage site to a virulent sequence.
Avian diseases - 1 Dec 2006
Wakamatsu Nobuko, King Daniel J, Seal Bruce S, Peeters Ben P H, Brown Corrie C
Abstract excerpt
The principal molecular determinant of virulence of Newcastle disease virus (NDV) is the amino acid sequence at the fusion cleavage activation site. To extend the understanding of the role of the fusion cleavage activation site in NDV virulence, the pathogenesis in chickens of a lentogenic LaSota...
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