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Article

A clinically significant interaction between tacrolimus and multiple proton pump inhibitors in a kidney transplant recipient.

Pediatric transplantation - 1 Sept 2012

Maguire Michelle, Franz Thaddeus, Hains David S

Abstract excerpt

The shared metabolism of PPIs and tacrolimus through the CYP enzyme system has been associated with clinically significant drug interactions, especially in patients who are classified as CYP 2C19 PMs. However, existing data are conflicting, indicating that a single mechanism does not account for all interactions. A drug interaction between tacrolimus and omeprazole, esomeprazole, but not lansoprazole, occurred in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21883747
DOI: 10.1111/j.1399-3046.2011.01559.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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A clinically significant interaction between tacrolimus and multiple proton pump inhibitors in a kidney transplant recipient.PMID 21883747Read ↗

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