Article
Microarray-based genomic profiling as a diagnostic tool in acute lymphoblastic leukemia.
Genes, chromosomes & cancer - 1 Dec 2011
Simons Annet, Stevens-Kroef Marian, El Idrissi-Zaynoun Najat, van Gessel Sabine, Weghuis Daniel Olde, van den Berg Eva, Waanders Esmé, Hoogerbrugge Peter, Kuiper Roland, van Kessel Ad Geurts
Abstract excerpt
In acute lymphoblastic leukemia (ALL) specific genomic abnormalities provide important clinical information. In most routine clinical diagnostic laboratories conventional karyotyping, in conjunction with targeted screens using e.g., fluorescence in situ hybridization (FISH), is currently considered as the gold standard to detect such aberrations. Conventional karyotyping, however, is limited in its resolution and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
