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Article

PEMT G523A (V175M) is associated with sporadic Alzheimer's disease in a Chinese population.

Journal of molecular neuroscience : MN - 1 Mar 2012

Bi Xiu-Hua, Zhao Hua-Lu, Zhang Zhen-Xin, Zhang Jun-Wu

Abstract excerpt

There is evidence that increased concentrations of circulating homocysteine are associated with Alzheimer's disease (AD). Phosphatidylethanolamine N-methyltransferase (PEMT) is an important catalyst involved in the production of homocysteine. We investigated the association of a functional single nucleotide polymorphism (rs7946) in PEMT with sporadic AD risk in a Han Chinese population that included 386 AD...

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Source

Identifiers

PMID: 21881829
DOI: 10.1007/s12031-011-9630-3

Genes

PEMT
APOE

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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