Article
Methionine synthase polymorphism is a risk factor for Alzheimer disease.
Neuroreport - 18 Jul 2003
Beyer Katrin, Lao José I, Latorre Pilar, Riutort Nadal, Matute Belinda, Fernández-Figueras M Teresa, Mate José L, Ariza Aurelio
Abstract excerpt
Alzheimer disease (AD) patients show increased plasma levels of homocysteine, whose conversion to methionine is catalyzed by methionine synthase (MS). Although altered MS activity may result from the MS A2756G polymorphism, the latter's possible associ-ation with AD remains unexplored. To assess whether the MS A2756G polymorphism holds any influence on AD risk, we have analyzed 172 AD patients and 166 controls....
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