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Article

Ob/ob serum promotes a mesenchymal cell phenotype in B16BL6 melanoma cells.

Clinical & experimental metastasis - 1 Dec 2011

Kushiro Kyoko, Núñez Nomelí P

Abstract excerpt

In 2009, malignant melanoma was responsible for approximately 9,000 deaths in the US. These deaths are often associated with aggressive metastasis to secondary sites such as the lungs. Epidemiological and animal studies suggest that obesity is a risk factor for melanoma. Others have shown that B16BL6 melanoma cells metastasize more aggressively in obese ob/ob than in lean mice. However, the mechanism by which...

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Source

Identifiers

PMID: 21879359
DOI: 10.1007/s10585-011-9418-4

Genes

MMP9
TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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