Article
Intercellular adhesion molecule-1 (ICAM-1) is upregulated in aggressive papillary thyroid carcinoma.
Annals of surgical oncology - 1 Mar 2012
Buitrago D, Keutgen X M, Crowley M, Filicori F, Aldailami H, Hoda R, Liu Yi-Fang, Hoda R S, Scognamiglio T, Jin M, Fahey T J, Zarnegar R
Abstract excerpt
BACKGROUND: Intercellular adhesion molecule-1 (ICAM-1) is implicated in carcinogenesis. In this study we examined the expression of ICAM-1 in papillary thyroid cancer (PTC). We hypothesized that ICAM-1 correlates with indicators of tumor aggressiveness in PTC. METHODS: Thirty-five primary and metastatic PTCs, five follicular adenomas, five Hashimoto thyroiditis, five nodular hyperplasia, and eight normal thyroid...
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