Article
Clinicopathological significance of major histocompatibility complex class I-related chain a and B expression in thyroid cancer.
The Journal of clinical endocrinology and metabolism - 1 Jul 2006
Xu Xiulong, Rao Geetha, Gaffud Michael J, Ding Helen G, Maki Guitta, Klingemann Hans-G, Groh Veronika, Spies Thomas, Caillat-Zucman Sophie, Gattuso Paolo, Plate Janet, Prinz Richard A
Abstract excerpt
CONTEXT: Major histocompatibility complex class I-related chains A and B (MICA/B) are two stress-inducible ligands for the immunoreceptor NKG2D that is expressed on cytotoxic T cells and natural killer (NK) cells. It is not known whether MICA/B expression is up-regulated in thyroid cancer as a result of oncogene activation. OBJECTIVE: The objective of the investigation was to study MICA/B expression and...
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