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Article

IQGAP1 plays an important role in the invasiveness of thyroid cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Dec 2010

Liu Zhi, Liu Dingxie, Bojdani Ermal, El-Naggar Adel K, Vasko Vasily, Xing Mingzhao

Abstract excerpt

PURPOSE: This study was designed to explore the role of IQGAP1 in the invasiveness of thyroid cancer and its potential as a novel prognostic marker and therapeutic target in this cancer. EXPERIMENTAL DESIGN: We examined IQGAP1 copy gain and its relationship with clinicopathologic outcomes of thyroid cancer and investigated its role in cell invasion and molecules involved in the process. RESULTS: We found IQGAP1...

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Source

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Identifiers

PMID: 20959410
DOI: 10.1158/1078-0432.CCR-10-1627
PMCID: PMC3005072

Genes

IQGAP1
BRAF
IQGAP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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