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Article

Novel measures of linkage disequilibrium that correct the bias due to population structure and relatedness.

Heredity - 1 Mar 2012

Mangin B, Siberchicot A, Nicolas S, Doligez A, This P, Cierco-Ayrolles C

Abstract excerpt

Among the several linkage disequilibrium measures known to capture different features of the non-independence between alleles at different loci, the most commonly used for diallelic loci is the r(2) measure. In the present study, we tackled the problem of the bias of r(2) estimate, which results from the sample structure and/or the relatedness between genotyped individuals. We derived two novel linkage...

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Identifiers

PMID: 21878986
DOI: 10.1038/hdy.2011.73
PMCID: PMC3282397

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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