Article
Decomposing multilocus linkage disequilibrium.
Genetics - 1 Mar 2004
Gorelick Root, Laubichler Manfred D
Abstract excerpt
We present a mathematically precise formulation of total linkage disequilibrium between multiple loci as the deviation from probabilistic independence and provide explicit formulas for all higher-order terms of linkage disequilibrium, thereby combining J. Dausset et al.'s 1978 definition of linkage disequilibrium with H. Geiringer's 1944 approach. We recursively decompose higher-order linkage disequilibrium terms...
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