Article
Natural variation within the principal adhesion domain of the Plasmodium vivax duffy binding protein.
Infection and immunity - 1 Dec 1994
Tsuboi T, Kappe S H, al-Yaman F, Prickett M D, Alpers M, Adams J H
Abstract excerpt
The blood-stage development of malaria parasites is initiated by the invasion of merozoites into susceptible erythrocytes. Specific receptor-ligand interactions must occur for the merozoites to first attach to and then invade erythrocytes. Because the invasion process is essential for the parasite's survival and the merozoite adhesion molecules are exposed on the merozoite surface during invasion, these adhesion...
Topics
- Amino Acid Sequence
- Animals
- Antigens, Protozoan
- Base Sequence
- Binding Sites
- Cell Adhesion
- Child
- Duffy Blood-Group System
- Genes, Protozoan
- Genetic Variation
- Humans