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DNA Extraction Columns Contaminated with Murine Sequences

18 Aug 2011

Abstract excerpt

Sequences of the novel gammaretrovirus, xenotropic murine leukemia virus-related virus (XMRV) have been described in human prostate cancer tissue, although the amounts of DNA are low. Furthermore, XMRV sequences and polytropic (p) murine leukemia viruses (MLVs) have been reported in patients with chronic fatigue syndrome (CFS). In assessing the prevalence of XMRV in prostate cancer tissue samples we discovered...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 21876752
DOI: 10.1371/journal.pone.0023484

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DNA Extraction Columns Contaminated with Murine SequencesPMID 21876752Read ↗

Mouse DNA contamination in human tissue tested for XMRVSemantic proximity Read ↗

Contamination of human DNA samples with mouse DNA can lead to false detection of XMRV-like sequencesSemantic proximity Read ↗

Contamination of clinical specimens with MLV-encoding nucleic acids: implications for XMRV and other candidate human retrovirusesSemantic proximity Read ↗

Disease-associated XMRV sequences are consistent with laboratory contaminationSemantic proximity Read ↗

In-depth investigation of archival and prospectively collected samples reveals no evidence for XMRV infection in prostate cancer.Semantic proximity Read ↗

No evidence of XMRV in prostate cancer cohorts in the Midwestern United States.Semantic proximity Read ↗

PCR Master Mixes Harbour Murine DNA Sequences. Caveat Emptor!Semantic proximity Read ↗

No association of xenotropic murine leukemia virus-related viruses with prostate cancer.Semantic proximity Read ↗

Multiple sources of contamination in samples from patients reported to have XMRV infection.Semantic proximity Read ↗

Xenotropic Murine Leukemia Virus–related Gammaretrovirus in Respiratory TractSemantic proximity Read ↗

Biology and pathophysiology of the new human retrovirus XMRV and its association with human disease.Semantic proximity Read ↗

Identification of Replication Competent Murine Gammaretroviruses in Commonly Used Prostate Cancer Cell LinesSemantic proximity Read ↗

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