Article
No evidence of XMRV in prostate cancer cohorts in the Midwestern United States.
Retrovirology - 29 Mar 2011
Sakuma Toshie, Hué Stéphane, Squillace Karen A, Tonne Jason M, Blackburn Patrick R, Ohmine Seiga, Thatava Tayaramma, Towers Greg J, Ikeda Yasuhiro
Abstract excerpt
BACKGROUND: Xenotropic murine leukemia virus (MLV)-related virus (XMRV) was initially identified in prostate cancer (PCa) tissue, particularly in the prostatic stromal fibroblasts, of patients homozygous for the RNASEL R462Q mutation. A subsequent study reported XMRV antigens in malignant prostatic epithelium and association of XMRV infection with PCa, especially higher-grade tumors, independently of the RNASEL...
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