Article
Validation of the association of genetic variants on chromosome 9p21 and 1q41 with myocardial infarction in a Japanese population.
Circulation journal : official journal of the Japanese Circulation Society - 1 Aug 2008
Hiura Yumiko, Fukushima Yasue, Yuno Miyuki, Sawamura Hiromi, Kokubo Yoshihiro, Okamura Tomonori, Tomoike Hitonobu, Goto Yoichi, Nonogi Hiroshi, Takahashi Rie, Iwai Naoharu
Abstract excerpt
BACKGROUND: Recent large-scale genome-wide association studies have identified several loci associated with the risk of coronary artery disease (CAD). The aim of the present study was to examine whether the previously reported CAD-associated single-nucleotide polymorphisms (SNPs) confer susceptibility to myocardial infarction (MI) in a study population of 2,475 controls and 589 cases of MI. The effect of the...
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