GCH1 (rs841) polymorphism in the nitric oxide-forming pathway has protective effects on obstructive sleep apnea.

doi:10.1038/s41598-019-55244-1

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Article

GCH1 (rs841) polymorphism in the nitric oxide-forming pathway has protective effects on obstructive sleep apnea.

Scientific reports - 9 Dec 2019

Sheikhi Kouhsar Samaneh, Bigdeli Mohammadreza, Shakiba Yadollah, Sadeghniiat Khosro

Abstract excerpt

Several studies have recently investigated the contribution of genetic factors in obstructive sleep apnea (OSA). Patients with OSA suffer from a reduction in nitric oxide (NO) serum level. This study investigated rs841, A930G p22phox, and rs1799983 polymorphisms in three critical genes involved in NO formation. A total of 94 patients with OSA and 100 healthy controls were enrolled into the study. Results showed...

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Identifiers

PMID: 31819149
DOI: 10.1038/s41598-019-55244-1
PMCID: PMC6901474

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