Article
GCH1 (rs841) polymorphism in the nitric oxide-forming pathway has protective effects on obstructive sleep apnea.
Scientific reports - 9 Dec 2019
Sheikhi Kouhsar Samaneh, Bigdeli Mohammadreza, Shakiba Yadollah, Sadeghniiat Khosro
Abstract excerpt
Several studies have recently investigated the contribution of genetic factors in obstructive sleep apnea (OSA). Patients with OSA suffer from a reduction in nitric oxide (NO) serum level. This study investigated rs841, A930G p22phox, and rs1799983 polymorphisms in three critical genes involved i...
Topics
- Adult
- Female
- GTP Cyclohydrolase
- Genetic Association Studies
- Genetic Predisposition to Disease
- Genotype
- Humans
- Male
- Middle Aged
- Nitric Oxide
- Polymorphism, Single Nucleotide
- Risk Factors
- Sleep Apnea, Obstructive