Article
Multilocus genotyping reveals a polyphyletic pattern among naturally antimony-resistant Leishmania braziliensis isolates from Peru.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Dec 2011
Adaui Vanessa, Maes Ilse, Huyse Tine, Van den Broeck Frederik, Talledo Michael, Kuhls Katrin, De Doncker Simonne, Maes Louis, Llanos-Cuentas Alejandro, Schönian Gabriele, Arevalo Jorge, Dujardin Jean-Claude
Abstract excerpt
In order to understand the epidemiological dynamics of antimonial (Sb(V)) resistance in zoonotic tegumentary leishmaniasis and its link with treatment outcome, we analyzed the population structure of 24 Peruvian Leishmania braziliensis clinical isolates with known in vitro antimony susceptibility and clinical phenotype by multilocus microsatellite typing (14 microsatellite loci). The genetic variability in the...
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