Article
Recruitment of bone marrow-derived valve interstitial cells is a normal homeostatic process.
Journal of molecular and cellular cardiology - 1 Dec 2011
Hajdu Zoltan, Romeo Stephen J, Fleming Paul A, Markwald Roger R, Visconti Richard P, Drake Christopher J
Abstract excerpt
Advances in understanding of the maintenance of the cardiac valves during normal cardiac function and response to injury have led to several novel findings, including that there is contribution of extra-cardiac cells to the major cellular population of the valve: the valve interstitial cell (VIC). While suggested to occur in human heart studies, we have been able to experimentally demonstrate, using a mouse...
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