Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Epitope analysis and protection by a ROP19 DNA vaccine against<i>Toxoplasma gondii</i>

1 Jan 2016

Abstract excerpt

We used bioinformatics approaches to identify B-cell and T-cell epitopes on the ROP19 protein of Toxoplasma gondii. Then, we constructed plasmids with ROP19 (pEGFP-C1-ROP19) and injected them into BALB/c mice to test the immunoprotection induced by this vaccine candidate. The results showed that immunization with pEGFP-C1-ROP19 induced effective cellular and humoral immune responses in mice; specifically, high...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Herpesvirus Infections and Treatments
Share to Parasitic Infections and Diagnostics
Share to Toxoplasma gondii Research Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27055564
DOI: 10.1051/parasite/2016017

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Epitope analysis and protection by a ROP19 DNA vaccine against<i>Toxoplasma gondii</i>PMID 27055564Read ↗

Protective Immune Response in BALB/c Mice Induced by DNA Vaccine of the ROP8 gene of Toxoplasma gondiiSemantic proximity Read ↗

Immunization With a DNA Vaccine Cocktail Encoding TgPF, TgROP16, TgROP18, TgMIC6, and TgCDPK3 Genes Protects Mice Against Chronic ToxoplasmosisSemantic proximity Read ↗

Protective Efficacy of a Toxoplasma gondii Rhoptry Protein 13 Plasmid DNA Vaccine in MiceSemantic proximity Read ↗

Induction of Protective Immune Responses by a Multiantigenic DNA Vaccine Encoding GRA7 and ROP1 of Toxoplasma gondiiSemantic proximity Read ↗

Protective effect against toxoplasmosis in mice induced by DNA immunization with gene encoding Toxoplasma gondii ROP18Semantic proximity Read ↗

A live attenuated RHΔompdcΔuprt mutant of Toxoplasma gondii induces strong protective immunity against toxoplasmosis in mice and catsSemantic proximity Read ↗

Evaluation of immune protection againstToxoplasma gondiiinfection in mice induced by a multi-antigenic DNA vaccine containing TgGRA24, TgGRA25 and TgMIC6Semantic proximity Read ↗

Bioinformatics analysis and expression of a novel protein ROP48 in Toxoplasma gondiiSemantic proximity Read ↗

Designing Diagnostic Kit for Toxoplasma gondii Based on GRA7, SAG1, and ROP1 Antigens: An In Silico StrategySemantic proximity Read ↗

Toxoplasma gondii virulence factor ROP1 reduces parasite susceptibility to murine and human innate immune restrictionSemantic proximity Read ↗

Live-attenuated Toxoplasma gondii PruΔpp2a-c mutant elicits protective immunity against toxoplasmosis in mice and catsSemantic proximity Read ↗

Genetic characterization of Toxoplasma gondii from human and chicken isolates from Argentina.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.