Article
Human adipose-derived stem cells impair natural killer cell function and exhibit low susceptibility to natural killer-mediated lysis.
Stem cells and development - 20 May 2012
DelaRosa Olga, Sánchez-Correa Beatriz, Morgado Sara, Ramírez Cristina, del Río Borja, Menta Ramón, Lombardo Eleuterio, Tarazona Raquel, Casado Javier G
Abstract excerpt
Human adipose-derived stem cells (hASCs) have been successfully used in treating numerous diseases. However, several aspects need to be considered, particularly in the context of allogeneic cell therapy. To better understand hASCs-host interactions, we studied the phenotype of hASCs and their modulatory effect on natural killer (NK) cells by using bone marrow-mesenchymal stem cells (hBM-MSCs) as a reference. The...
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