Article
Mesenchymal stem cells derived from adipose tissue are not affected by renal disease.
Kidney international - 1 Oct 2012
Roemeling-van Rhijn Marieke, Reinders Marlies E J, de Klein Annelies, Douben Hannie, Korevaar Sander S, Mensah Fane K F, Dor Frank J M F, IJzermans Jan N M, Betjes Michiel G H, Baan Carla C, Weimar Willem, Hoogduijn Martin J
Abstract excerpt
Mesenchymal stem cells are a potential therapeutic agent in renal disease and kidney transplantation. Autologous cell use in kidney transplantation is preferred to avoid anti-HLA reactivity; however, the influence of renal disease on mesenchymal stem cells is unknown. To investigate the feasibility of autologous cell therapy in patients with renal disease, we isolated these cells from subcutaneous adipose tissue...
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