Article
Apolipoprotein E polymorphisms and sleep quality in obstructive sleep apnea syndrome.
Clinica chimica acta; international journal of clinical chemistry - 20 Nov 2011
Pellegrino R, Mazzotti D R, Guindalini C, Santos-Silva R, Bittencourt L R A, Tufik S
Abstract excerpt
BACKGROUND: The purpose of this study was to evaluate the influence of polymorphism on sleep parameters of Obstructive Sleep Apnea Syndrome (OSAS) patients. METHODS: Patients were genotyped after a full-night polysomnography using the large Epidemiologic Sleep Study of São Paulo population-based sample. RESULTS: Individuals who carry the APOE ε2 allele showed longer sleep latency, lower sleep efficiency and...
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