Article
APOE epsilon4 is associated with obstructive sleep apnea/hypopnea: the Sleep Heart Health Study.
Neurology - 24 Aug 2004
Gottlieb D J, DeStefano A L, Foley D J, Mignot E, Redline S, Givelber R J, Young T
Abstract excerpt
BACKGROUND: Obstructive sleep apnea/hypopnea (OSAH) has a strong heritable component, although its genetic basis remains largely unknown. One epidemiologic study found a significant association between the APOE epsilon4 allele and OSAH in middle-aged adults, a finding that was not replicated in a...
Topics
- Adult
- Age Distribution
- Aged
- Aged, 80 and over
- Alleles
- Apolipoprotein E4
- Apolipoproteins E
- Cardiovascular Diseases
- Cohort Studies
- Comorbidity
- Female
- Genetic Predisposition to Disease
- Genotype
- Humans
- Hyperlipidemias
- Hypertension
- Male
- Middle Aged