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Article

APOE epsilon4 is associated with obstructive sleep apnea/hypopnea: the Sleep Heart Health Study.

Neurology - 24 Aug 2004

Gottlieb D J, DeStefano A L, Foley D J, Mignot E, Redline S, Givelber R J, Young T

Abstract excerpt

BACKGROUND: Obstructive sleep apnea/hypopnea (OSAH) has a strong heritable component, although its genetic basis remains largely unknown. One epidemiologic study found a significant association between the APOE epsilon4 allele and OSAH in middle-aged adults, a finding that was not replicated in a cohort of elderly adults. The objective of this study was to further examine the association of the APOE epsilon4...

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Source

Identifiers

PMID: 15326239
DOI: 10.1212/01.wnl.0000134671.99649.32

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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