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Article

DEspR T/CATAAAA-box promoter variant decreases DEspR transcription and is associated with increased BP in Sardinian males.

Physiological genomics - 7 Nov 2011

Glorioso Nicola, Herrera Victoria L M, Didishvili Tamara, Argiolas Giuseppe, Troffa Chiara, Bulla Patrizia, Bulla Emanuela, Ruiz-Opazo Nelson

Abstract excerpt

Essential hypertension is highly prevalent in the elderly population, exceeding 70% in people older than 60 yr of age, and remains a leading risk factor for heart disease, stroke, and chronic renal disease. Elucidation of genetic determinants is critical but remains a challenge due to its complex, multifactorial pathogenesis. We investigated the role DEspR promoter variants, previously associated with male...

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Identifiers

PMID: 21862670
DOI: 10.1152/physiolgenomics.00012.2011
PMCID: PMC3217322

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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