Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Functional characterization of CaCBF1, the Candida albicans homolog of centromere binding factor 1.

Gene - 24 Dec 2003

Biswas Kajal, Rieger Klaus Jörg, Morschhäuser Joachim

Abstract excerpt

The centromere binding factor 1 (Cbf1) is necessary for proper chromosome segregation and transcriptional activation of methionine biosynthesis genes in the yeast Saccharomyces cerevisiae and is essential for viability in the related yeasts Kluyveromyces lactis and Candida glabrata. To study the function of Cbf1p in Candida albicans, the major human fungal pathogen, we constructed strains in which both alleles of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Candida albicans
Share to Chromosomal Instability
Share to Chromosome Deletion

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosome Segregation

Share to Chromosomes, Fungal

Share to Cysteine

Share to Fungal Proteins

Share to Methionine

Source

Identifiers

PMID: 14659878
DOI: 10.1016/j.gene.2003.09.005

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Functional characterization of CaCBF1, the Candida albicans homolog of centromere binding factor 1.PMID 14659878Read ↗

The centromere-binding factor Cbf1p from Candida albicans complements the methionine auxotrophic phenotype of Saccharomyces cerevisiae.Semantic proximity Read ↗

Multifunctional centromere binding factor 1 is essential for chromosome segregation in the human pathogenic yeast Candida glabrata.Semantic proximity Read ↗

Yeast centromere binding protein CBF1, of the helix-loop-helix protein family, is required for chromosome stability and methionine prototrophy.Semantic proximity Read ↗

Point mutations that separate the role of Saccharomyces cerevisiae centromere binding factor 1 in chromosome segregation from its role in transcriptional activation.Semantic proximity Read ↗

CDP1, a novel Saccharomyces cerevisiae gene required for proper nuclear division and chromosome segregation.Semantic proximity Read ↗

Functional mapping of the Candida albicans Efg1 regulator.Semantic proximity Read ↗

The CENP-A homolog CaCse4p in the pathogenic yeast Candida albicans is a centromere protein essential for chromosome transmission.Semantic proximity Read ↗

Identification and characterization of a highly conserved calcineurin binding protein, CBP1/calcipressin, in Cryptococcus neoformans.Semantic proximity Read ↗

Molecular cloning of CIF1, a yeast gene necessary for growth on glucose.Semantic proximity Read ↗

Bdf1, a yeast chromosomal protein required for sporulation.Semantic proximity Read ↗

Functional redundancies, distinct localizations and interactions among three fission yeast homologs of centromere protein-B.Semantic proximity Read ↗

Determination of the binding constants of the centromere protein Cbf1 to all 16 centromere DNAs of Saccharomyces cerevisiae.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.