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Article

Characterization of DOK1, a candidate tumor suppressor gene, in epithelial ovarian cancer.

Molecular oncology - 1 Oct 2011

Mercier Pierre-Luc, Bachvarova Magdalena, Plante Marie, Gregoire Jean, Renaud Marie-Claude, Ghani Karim, Têtu Bernard, Bairati Isabelle, Bachvarov Dimcho

Abstract excerpt

In attempt to discover novel aberrantly hypermethylated genes with putative tumor suppressor function in epithelial ovarian cancer (EOC), we applied expression profiling following pharmacologic inhibition of DNA methylation in EOC cell lines. Among the genes identified, one of particular interest was DOK1, or downstream of tyrosine kinase 1, previously recognized as a candidate tumor suppressor gene (TSG) for...

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Share to Carcinoma, Ovarian Epithelial
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21856257
DOI: 10.1016/j.molonc.2011.07.003
PMCID: PMC5528302

Genes

DOK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Characterization of DOK1, a candidate tumor suppressor gene, in epithelial ovarian cancer.PMID 21856257Read ↗

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