Article
Pro12Ala PPAR gamma2 gene polymorphism in women with polycystic ovary syndrome.
Ginekologia polska - 1 Jun 2011
Bidzińska-Speichert Bozena, Lenarcik Agnieszka, Tworowska-Bardzińska Urszula, Slezak Ryszard, Bednarek-Tupikowska Grazyna, Milewicz Andrzej, Krepuła Katarzyna
Abstract excerpt
INTRODUCTION: The pathogenesis of PCOS has not been definitively determined and includes a number of genes linked with steroidogenesis, regulation of gonadotropin secretion, actions of insulin, obesity as well as chronic inflammatory processes. Some authors indicate that PPARgamma play a role in insulin sensitivity and are probably involved in hyperandrogenism in PCOS. The aim of the study was to assess the...
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