Article
Pro12Ala and His447His polymorphisms of PPAR-gamma are associated with polycystic ovary syndrome.
Reproductive biomedicine online - 1 May 2009
Gu Bon-Hee, Baek Kwang-Hyun
Abstract excerpt
Polycystic ovary syndrome (PCOS) is a common endocrine disorder that affects 4-12% of women of reproductive age, and is specified when two of the three following criteria are present: hyperandrogenism, oligomenorrhoea and polycystic ovary morphology by ultrasonography. PCOS is characterized by infertility, obesity and hyperinsulinaemia. However, the aetiology of PCOS has not yet been fully identified due to...
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